Name: Gabon researchers test promising single-dose malaria treatment
Uploaded: 2025-11-13T22:04:15.438Z
Duration: 2 min 10 s
Description: For many Gabonese, malaria remains a constant struggle. Libreville resident Julicia Nfono says the disease keeps coming back despite preventive measures.

For many Gabonese, malaria remains a constant struggle. Libreville resident Julicia Nfono says the disease keeps coming back despite preventive measures.

Libreville

Researchers at the Medical Research Center of Lamborghini in Gabon, led by Dr. Ghislain Mambunguma, have tested a single-dose malaria treatment that combines four widely available anti-malaria compounds. The treatment cleared malaria parasites in 93 percent of patients, a success rate comparable to the current three-day regimen.

Malaria remains a significant public health issue in Gabon, with over 154,000 cases reported in 2024 and particularly high incidence among children under five. The single-dose approach is expected to improve treatment compliance, reduce resistance, and make malaria care more accessible in heavily affected communities.

Gabon researchers test promising single-dose malaria treatment

Doctors in Gabon say a single-dose malaria treatment could help curb the disease's growing resistance to existing drugs. Led by Dr. Ghislain Mambunguma at the Medical Research Center of Lamborghini, researchers tested a one-time treatment combining four widely available anti-malaria compounds. At the moment, it was observed that the morbidity and mortality of malaria is going up. And for that, we need solutions now. As we need solutions now, so we thought, why not make the most of existing anti-malarial drugs? The new drug, clad malaria parasite, in 93 percent of patients, matching the success of the standard three-day regimen. Every time I go to the hospital, they diagnose me with malaria. After treatment and follow-up, of course, it always comes back. So it's better to protect ourselves. We need mosquito nets. We protect ourselves from dirty water. As long as there are mosquitoes, it will always come back. For many Gabonese, malaria remains a constant struggle. Program official calls malaria a major public health problem. Malaria is a major public health problem in our country. That is, according to 2024 data, more than 154,000 cases with an incidence of 62 per 1,000 inhabitants in the general population. Unfortunately, when you take a closer look and look at children under five, this incidence increases to 112 per 1,000 inhabitants. The single-dose approach could help improve treatment compliance, reduce resistance, and make malaria care more accessible in Africa's most affected communities.

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