Researchers at the University of Queensland are exploring venom peptides from some of the countries deadliest spiders and scorpions as a potential treatment for drug-resistant epilepsy.

Brisbane

A young man named Seth, who has a rare form of drug-resistant genetic epilepsy, is among the 30% of patients for whom traditional anti-seizure medications are ineffective. Researchers at the University of Queensland have identified that venom from some of Australia's deadliest arachnids, including funnel-web spiders and tarantulas, could be used to develop precision therapies for these patients.

The research is still in the preclinical stage, with scientists testing the effectiveness and safety of venom-based treatments before moving to human trials. The ultimate goal is to reduce premature deaths and improve the quality of life for people with drug-resistant epilepsy, offering hope to patients and their families.

Spider venom offers hope for drug-resistant epilepsy

It's been a long and challenging road for Seth and his family. Epilepsy's not fun. There's a lot of... I wouldn't say too many ups, but there's a lot of downs. The 22-year-old has a rare drug-resistant genetic epilepsy, which affects around 30% of patients. Seizures can be life-threatening. I think I just go into fight-or-flight mode, and then I lose it later. What I see is this really long and tumultuous journey of trial and error of anti-seizure medications. And now we can actually identify the causes for some epilepsies. And it's all thanks to these creatures, some of Australia's deadliest arachnids, funnel-webs and tarantulas. Researchers at the University of Queensland have discovered the venom in spiders can provide precision therapy for patients resistant to treatment. And it's not just spiders, it's scorpions too. Researchers are looking into the venom treatment, testing the effectiveness and safety before heading into human trial. Premature death. So my main aim would be also to reduce death. Give them some hope, better quality of life. Um... Stop the parents, I guess, from living in fear. Brittany Lane, 10 News.

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