Sanofi has reached an agreement in principle to settle 4,000 U.S. lawsuits linking the discontinued heartburn drug Zantac to cancer, the company said.

Washington

Sanofi, a global healthcare leader, has announced an agreement in principle to resolve approximately 4,000 lawsuits in the United States. These legal actions have connected the use of Zantac, a once-popular heartburn medication, to cancer risks, leading to its discontinuation. The company stated its commitment to resolving these claims, though specific terms of the settlement were not disclosed.

The lawsuits represent a significant legal challenge for Sanofi, focusing on allegations that Zantac was responsible for causing cancer in patients who used the drug. The settlement is seen as a pivotal move to address these concerns and possibly conclude a chapter of legal disputes surrounding the medication's safety.



Sanofi to settle thousands of Zantac cancer lawsuits

French pharmaceutical giant Sanofi has reached a tentative agreement to settle thousands of U.S. lawsuits, which link their heartburn pill Zantac to cancer. Sanofi did not disclose financial details of the deal, nor admit any liability in the settlement over the drug, which is now discontinued. The company said it is settling to avoid the expense and ongoing distraction of the litigation. The agreement, which still needs to be finalized, would resolve most of the lawsuits against the firm in U.S. state courts, around 4,000 of them. That's with the exception of Delaware, where 20,000 suits over the heartburn pill are still pending. Zantac was first approved in 1983 and soared to become one of the most popular drugs in the world. Then, after the carcinogenic chemical NDMA was found in some pills, the U.S. Food and Drug Administration asked manufacturers to pull the drug off the market in 2020. Sanofi has maintained there is no evidence Zantac exposed users to harmful levels of NDMA. The drugmaker now sells the reformulated heartburn medicine Zantac 360.

The bodies Australian brothers, Jake and Callum Robinson have been identified by authorities in Baja California, Mexico. It comes as their grieving parents arrive in the country.

Council of the City of Sydney

Brothers identified as victims of Mexico robbery

Qantas has been ordered to compensate passengers following revelations that it sold tickets on thousands of flights that had already been cancelled. The airline has agreed to pay a $100 million fine and $20 million in compensation to affected passengers.

Mascot

Qantas ordered to pay compensation over 'ghost flight' scandal

A former detective is facing allegations of sexually assaulting a 19-year-old woman whose case he was initially assigned to investigate. Accused of exploiting his authority, Glenn Coleman, 55, has been charged with 10 offences,

Penrith

Police officer accused of assaulting rape victim

The death toll from heavy rains that have caused flooding in Brazil's southern state of Rio Grande do Sul has risen to at least 78, local authorities said, with more than 115,000 people displaced.

State of Rio Grande do Sul

Climate Crisis

Death toll rises in record-breaking Brazil floods

China's President Xi Jinping has arrived in France for a rare visit with President Emmanuel Macron. They are set to discuss trade, amid growing tension between Europe and China over an imbalance between China's exports and European imports.

Paris

China's Xi Jinping visits Europe amid global tensions

While several pro-Palestinian campus protests in the U.S. were dismantled over the weekend, others became more disruptive and interrupted at least one graduation ceremony.

Chicago

Protests disrupt graduation ceremonies at U.S. universities

Prospects for a Gaza ceasefire appeared slim as Hamas reiterated its demand for an end to the war in exchange for the freeing of hostages, and Israeli Prime Minister Benjamin Netanyahu flatly ruled that out.

Tel Aviv-Yafo

Israel-Gaza War

Gaza truce hopes fade as Israel, Hamas trade blame

The Israeli cabinet has voted to unanimously shut down Al Jazeera's operations in the country. That's according to Prime Minister Benjamin Netanyahu in a statement on X. 
It is not clear when this decision will take effect.

Israel announces ban of Al Jazeera channel, website

Australian police said they have shot dead a boy after he stabbed a man in Western Australia's capital Perth, in an attack authorities said indicated terrorism.

Perth

Australian police shoot boy dead after stabbing

Sadiq Khan has been elected mayor of London, winning a historic third term after a dramatic contest. Khan was declared the winner over the Conservative candidate, Susan Hall with 43.8% of the vote.

London

Sadiq Khan elected London mayor for third term

Floods have killed at least 58 people in southern Brazil. Nearly 70,000 have been forced from their homes. Tens of thousands of people have been left without drinking water or electricity. It's the worst flooding the region has seen in more than 80 years.

'It's going to get worse': Brazil braces for flood peaks

Students at the University of California in Irvine say they will remain on campus until all their demands are met. School officials say they'll continue to negotiate with the protesters -- and are hoping to reach a deal soon.

Irvine

Police, protesters in stand-off at California university

The Federal Government will cut $3 billion in student debts, in measures to be announced in next week's budget. The reforms will see the student loans of three million graduates by an average of $1200 and changes to loan indexation.

Camperdown

Labor to wipe $3 billion of student debts

Mexican authorities have charged three suspects over the disappearance of Australian brothers Callum and Jake Robinson and their American friend Jack Carter Rhoad. It's believed the tourists became embroiled in a bungled robbery. Four bodies were found near the trio's abandoned campsite, but are yet to be formally identified.

Baja California

Mexican authorities lay charges over Australian brothers' disappearance

A knife-wielding teenage boy has been shot dead by police in Bunnings carpark in Willetton, Perth. The 16-year-old boy had phoned Triple Zero saying he planned ‘acts of violence’ and stabbed a male member of the public. The WA Police Commissioner says the teenager had ‘mental health and radicalisation issues’.

Willetton

Police shoot dead ‘radicalised’ teenage boy in Perth

The death toll from rains in Brazil's southernmost state of Rio Grande do Sul rose to 57, local authorities said on Saturday (May 4) afternoon, while dozens still have not been accounted for.

Dozens missing amid record-breaking Brazil flooding

There are renewed hopes for a ceasefire in Gaza after a Hamas delegation arrived in Cairo to continue talks amid reports of a proposal agreed to by Israel to halt fighting for an initial 40 days in exchange for the release of hostages.

Hopes rise for Gaza ceasefire amid Hamas talks

Students showing support for Palestinians have set up camp outside the University College London. They say they'll continue their protest until the university divests from Israeli institutions that 'profit from the war in Gaza'.

Pro-Palestine university protests spread to London

Dozens of Palestinians have held a demonstration in the West Bank, to condemn the killing of five Palestinian fighters. Crowds rallied hours after Israeli troops attacked the fighters in the village of Deir al Ghoson.

Jerusalem

Five Palestinian fighters killed during West Bank raid

Dozens of people in two rubber dinghies have reached the southern coast of England, the latest among thousands of asylum-seeking migrants to make the risky sea crossing from France this year.

Dover

Asylum seekers arrive in England despite Rwanda threat

A former immigration detainee has been bailed after allegedly threatening police with a knife in Melbourne. It follows the recent violent home invasion allegedly committed by another released detainee in Western Australia Pressure is mounting on Federal Immigration Minister Andrew Giles to be held to account.

Canberra

Pressure mounts on Immigration Minister after latest detainee incident

Mexican authorities have reportedly discovered a fourth body near the cliff site where Perth brothers Jake and Callum Robinson disappeared, along with their American friend Jack Carter Rhoad. The Australian family of the brothers are en route to Mexico. The bodies are yet to be formally identified.

Ensenada

Fourth body discovered in Mexico search for Australian brothers

Ukraine is eagerly waiting for Western aid as Russia racks up more victories on the battlefield. Meanwhile, British Foreign Secretary David Cameron on a visit to Kyiv gave Ukraine the go-ahead to use British weapons to strike directly at Russia.

Kyiv

Ukraine Invasion

U.K. allows its weapons to be used on Russian soil

Canadian police have charged three Indian men with the murder of Sikh separatist leader Hardeep Singh Nijjar last year and said they were probing whether the men had ties to the Indian government.

Surrey

Canada police charge three with murder of Sikh leader

China has launched an uncrewed spacecraft on a nearly two-month mission to retrieve rocks and soil from the far side of the moon, the first country to make such an ambitious attempt.

Wenchang

China launches mission to far side of the moon

Britain's opposition Labour Party won a parliamentary seat in northern England on Friday (May 3) and control of several councils, inflicting heavy losses on the governing Conservatives to pile more pressure on Prime Minister Rishi Sunak.

U.K.'s Labour claims big early win over Conservatives

Turkey has announced that it is halting trade with Israel, worth $7 billion a year, until a permanent ceasefire and humanitarian aid are secured in Gaza. Israel denounced the decision as breaking trade agreements.

Ankara

Turkey to stop trade with Israel until Gaza ceasefire

Media watchdog group Reporters Without Borders warned of declining government support for press freedom as it unveiled its annual world rankings on Friday, highlighting Argentina among the countries where the situation has deteriorated.

States doing less to support press freedom, says watchdog

Arizona's Democratic governor signed a bill overturning an 1864 law banning abortion, a month after the state's supreme court said the Civil War-era rule was valid.

Arizona

Arizona governor signs bill repealing 1864 abortion ban

U.S. President Joe Biden said that both freedom of speech and the rule of law must be respected in protests at college campuses over Israel's war in Gaza. In response to a reporter's question, Biden said that the campus protests had not forced him to reconsider his policies in the Middle East.