Name: FDA approves Eli Lilly weight loss pill
Uploaded: 2026-04-02T02:18:18.076Z
Duration: 2 min 12 s
Description: The Food and Drug Administration has approved Eli Lilly’s GLP‑1 weight‑loss pill, making it the second oral GLP‑1 medication approved specifically for weight loss to enter the evolving obesity drug market.

The Food and Drug Administration has approved Eli Lilly’s GLP‑1 weight‑loss pill, making it the second oral GLP‑1 medication approved specifically for weight loss to enter the evolving obesity drug market.

New York

The U.S. Food and Drug Administration has approved Foundeo, an oral weight loss medication developed by Eli Lilly. Foundeo is the second oral GLP-1 drug for weight loss and the first that does not require fasting before use. Clinical trials showed that Foundeo reduced body weight by 7.5% to 11.2%, depending on the dose, though this is somewhat less than injectable GLP-1 drugs, which can lower weight by 15-20%.

The medication will be available for shipping beginning April 6, with costs ranging from $149 to $349 per month for uninsured patients, $50 for Medicare patients, and as low as $25 for some with private insurance. The most common side effects were gastrointestinal, and about 10% of patients on the highest dose discontinued use due to side effects. Experts note that weight regain can occur after stopping GLP-1 drugs, raising questions about long-term obesity prevention strategies.

FDA approves Eli Lilly weight loss pill

The FDA has approved a new weight loss medication in pill form, potentially expanding access to people who don't like needles, and there are a lot of them. Here is CBS News Chief Medical Correspondent, Dr. John Lapuk. The Eli Lilly drug, Foundeo, is the second oral GLP-1 for weight loss, and the first that does not need to be taken on an empty stomach. We want to make treatment of obesity as simple and easy for people as possible. Dr. Daniel Skowronski is the company's chief scientific officer. It really fits into people's lives in the same way that medicines they take for other conditions on a daily basis could fit in. That's a big advance. In a large clinical trial, Foundeo lowered body weight from an average of 7.5 percent at the lowest dose to 11.2 percent at the highest. Current injectable GLP drugs can lower weight by about 15 to 20 percent. Do you think people are going to switch from the injectable format? There may be some people who don't like taking a weekly injectable, but I think the big opportunity here is to democratize treatment of obesity for more patients, people who haven't had access to the injectable or haven't wanted to be on it, to introduce them to the pill and start them on therapy. The most common side effects were gastrointestinal. About 10 percent of those taking the highest dose stopped because of side effects. Weight loss for so long. I felt stuck. Lilly says it will start shipping Foundeo on April 6th, and pricing will be in line with other GLP-1 options. For people without insurance, the drug cost will start at $149 per month, going as high as $349, depending on dose. For Medicare patients, monthly cost is expected to be $50, and for eligible people with private insurance, as little as $25. One drawback to the GLP-1 drugs is that people tend to regain weight when they stop the medication. That raises a big question. As we treat millions of people at a cost of billions of dollars, what's the strategy for preventing future generations from becoming obese in the first place? Dr. John Lepook, CBS News, New York.

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