Name: Novartis reveals new drug to fight malaria resistance, transmission
Uploaded: 2025-11-14T21:11:24.289Z
Duration: 1 min 57 s
Description: Swiss pharmaceutical giant Novartis has unveiled a next-generation malaria treatment that not only demonstrates a 97% cure rate but also blocks disease transmission, representing a potential breakthrough in combating drug-resistant strains of the deadly parasite.

Swiss pharmaceutical giant Novartis has unveiled a next-generation malaria treatment that not only demonstrates a 97% cure rate but also blocks disease transmission, representing a potential breakthrough in combating drug-resistant strains of the deadly parasite.

Novartis has announced the development of GANLAM, a next-generation malaria drug identified after testing millions of compounds. Studies conducted across 12 African countries indicate that GANLAM is effective not only in treating malaria but also in inhibiting the transmission of the parasite, including strains resistant to existing therapies.

The findings were presented at the American Society of Tropical Medicine and Hygiene conference in Toronto. According to the World Health Organization, malaria remains a major health threat, causing nearly 600,000 deaths annually, predominantly among children in sub-Saharan Africa.

Novartis reveals new drug to fight malaria resistance, transmission

This high-speed robot has tested millions of compounds before arriving at what Novartis refers to as its next-generation treatment, GANLAM. A study conducted in 12 African countries revealed that it not only effectively combats the mosquito-borne parasite responsible for malaria, but also appears to inhibit its spread. So really, this has a potential to not just treat the disease, but also to work against the resistant parasites, additionally block the transmission of the disease. The findings of this study were presented on Wednesday at the American Society of Tropical Medicine and Hygiene conference in Toronto. This single-dose cure is going to be the holy grail, but it will take some time before we get there and resistance is developing, there is a need for this non-artemisinin-based drugs. So as we work towards the single dose, we are very happy to have this one. Malaria is caused by a parasite transmitted through mosquito bites whose treatment has seen fluctuations as new medications emerge while the parasite gradually acquires resistance. That's exciting because, and we're still worried, one of the combinations, there's resistance to both of the drugs and wondering, it still may work in many places in Africa where it's needed to save lives, but it's less exciting because it may not last quite as long as this novel drug class that works on all stages and lasts a long time. According to the World Health Organization, the mosquito-borne parasite claims nearly 600,000 lives annually, primarily in sub-Saharan Africa, with the majority of fatalities being children.

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